drug doses to know in medical

LIST of important drugs and doses

 IV hydrocot 200mg stat

S/c Fondaparinox 2.5mg OD/7.5mg OD

S/c Heparin 5000u BD/7500u BD

S/c Morphine 5mg/7.5mg TDS

S/c Clexane 40mg/60mg OD

T Ranitidine 150mg BD

IV Ranitidine 50mg TDS

Mist calminative 15mls TDS

Mist Na Citrate 15mls/30mls OD

T EES 400mg BD

T Zinnat 250mg BD

T Ponstan 500mg TDS

T Voltaren  50mg TDS

T Papase 11/11 TDS

T Gelusil 11/11 TDS

IV Maxolon 10mg TDS

C Celebrex 200mg BD /400mg OD

C Tramal 50mg/75mg TDS 

T Arcoxia 90mg OD

Syp MMT 15mls TDS

Syp Benadryl 15mls TDS

T Piriton 4mg/8mg TDS

IV hydrocortisone 200mg stat, 100mg QID

T Cilostazol (claudication pain) 100mg OD

T Aspirin 150mg OD/300mg STAT

IM nubain 20mg stat

T/IV Bisolvon 8mg TDS 

T Labetolol 100mg TDS 

T Adalat 10mg TDS

T Methyldopa 250mg TDS

Ural sachet 1/1 BD/TDS 

IV/T lasix 20/40/80 mg BD

IM/IV Pethidine 50mg

T Rocaltriol 0.25 mcg OD

T calcium lactate 600mg BD

T levenogestrel 1.5mg stat

Inj Ertapenem 1gm OD

Inj Piptaz 3.375g 

T/IV Tranexamic acid 500-1000mg TDS

IV Tramal 50 mg/75mg TDS

IV Maxolon 10 mg TDS

IV Cefuroxime 1.5 stat, 750mg TDS

IV Unasyn 1.5g STAT and TDS

IV Cefobid 2g stat, 1g BD

IV Ceftriaxone 2g stat, 2g/1g OD

IV Cefepime 2g stat, 1g BD

IV Meropenem 500mg tds/qid

IV Imipenem 500mg tds/qid

IV Ampicillin 2gm Stat 1gm QID

IV Cloxacillin 1g STAT, 1g/500mg QID

IV Flagyl 500mg TDS

IV Augmentin 1.2g STAT, TDS

T Augmentin 625 mg BD

T Unasyn 375mg BD

T Doxycycline 200mg stat, 100mg bd

T Cloxacillin 500mg QID

T Azithromycin 500mg OD

T Flagyl 400mg TDS

C Tramal 50mg/75mg TDS

T Maxolon 10mg TDS

T Doxazosin 4mg OD 

T Finasteride 5 mg OD

T Cardura 4mg ON

T Hytrin 4mg ON

T. Metoprolol 50mg BD

IV vancomycin 500mg QID/1g BD over 1hr40min - MRSA  

Cream chlophelamine 

T. Cetrizine 10mg stat and OD

LYTIC COCKTAIL

IV Actrapid 10u STAT

IV ca gluconate 10% 10cc in 10 minutes

IV Dextrose 50% 50cc

FAST CORRECT

IV KCL 2g/1g in 200cc/100cc over 1 hour/2 hour

IV KH2PO4 1 ampoule in 250cc NS/4H

IV Mgso4 1 ampoule in 100cc NS/4H

SEDATION

Midazolam 0.1mg/kg

Syrup chlorhydrate 50mg/kg

OAC/PAC REGIME

C Omeprazole 40mg BD

T Ampxicillin 1g BD

T Clarithromycin 500mg BD

Then C Omeprazole 40mg OD

HEMATINICS

T FeSO4 200/400mg OD/BD

T Vit B Co I/I, II/II OD/BD

T Folate I/I, II/II OD/BD

BOWEL PREP

2 days before - low residual diet

1 days before:

RP normal - fleet phosphosoda 45ml BD x 1/7

RP abnormal - Foltran 2L/3L

On day of scope:

Ravin enema II/II stat

Or fleet enema I/I stat

Do PR!

Tab. Daflone ll/ll TDS  4/7

Tab. Daflone ll/ll BD  3/7

Tab. Daflone ll/ll OD 1/52

*Antithrombotic:*

*1) Antiplatelet*

Oral:

a) Aspirin

b) P2Y12 inhibitors eg: clopidogrel, ticagrelor

Parenteral:

c) Glycoprotein IIb/IIIa inhibitors eg: abciximab

2) Anticoagulant

A)Oral

a) Vit K antagonist: Warfarin [Antidote: Vit K]

A) DOAC/NOAC

i) Direct Thrombin inhibitor: Dabigatran [Antidote: Idarucizumab]

ii) Anti Xa: Rivaroxaban/Apixaban/Edoxaban [Antidote: andexanet Alfa]

B) Parenteral

a) UFH [antidote: protamine sulfate]

b) LMWH [antidote: protamine sulfate]

c) synthetic Heparin: s/c Fondaparinux 2.5mg od 

d) Direct thrombin inhibitor: argatroban; bivalirudin

3) Thrombolytic agent

a) IV Streptokinase 1.5MU in NS run over 1hr

b) rtPa eg: Alteplase (use in acute ischemic stroke thrombolysis); Tenecteplase (use in acute MI, unstable acute PE)

Insulin

A) Conventional

i) Basal ( Intermediate acting)

- cover fasting glucose

eg: insulatard (NPH)/ Insuman N/Humulin N

- titrate: based on preBF CBS

- Dose: 0.2u/kg or 40-50% of TDD(total daily insulin dose)

-OD or BD

ii) Bolus/prandial (Short acting insulin eg: Actrapid/Humulin R)

- cover prandial glucose

- dose: 0.1u/kg or 50-60% from TDD

- must b given : 15-30min before main meal

- can titrate based on preprandial/prebed CBS after 24-72hrs of monitoring

iii) Premix

Eg mixtard (NPH+Actrapid)/insuman Combo

- dose max 2x/day...0.2u/kg or using TDD÷2

 

B) Analogue

i) Basal (long acting)

- glargine/levemir

- dose same as NPH

-OD dose

- indicated if pt has early morning hypo in pt with NPH ---> refer endocrine

ii) Bolus/prandial

- ultra short@rapid insulin

- glulisine(aphidra)/aspart(novorapid)/lispro(humalog)

iii) premix

Novomix

- can give upto TDS

Efficacy for diabetic therapy just the same, but conventionals are cheaper but more hypos and difficult in the timing of injection

Analogues are walletitis but more flexible in the timing of injection and for the long acting less hypo compare to NPH